Research of clinical effect of Dami safety oropharyngeal airway

Doctors from The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China made a study to explore the safety and effectiveness of the “Dami safety oropharyngeal airway”, and published the study in Journal Clin Anesthesiol, July 2020, Vol.36,No.7

Clinical effect of Dami weakly stimulated oropharyngeal pad on patients undergoing general anesthesia in recovery period

By XIA Min, ZHANG Wei, TAO Lei, CHAI Xiaoqing and other four authors.

[Abstract]  Objective  To explore the clinical significance of Dami weakly stimulated oropharyngeal pad (Dami airway) as an innovative transitional airway in patients undergoing general anesthesia with endotracheal intubation.

Methods  A total of 200 patients, 153 males and 47 females, aged 26-66 years, weighing 42-91kg, ASA physical status I-Ⅲ, who underwent general anesthesia with endotracheal intubation and incomplete recovery of consciousness, falling back of tongue or poor breathing after extubation were selected. Randomly divided into four groups, 50 cases in each group: group D, group K, group B and group C. After extubation, airway management measures were as follows: in group D, the mouth pad with weak stimulation of Dami airway was put into the mouth; in group K, the mouth pharynx airway was put into the mouth; in group B, the nasopharynx airway was put into the nose; in group C, when airway obstruction occurred, the mouth pad was put into the mouth. The hemodynamic indexes (HR, BP, SpO2), blood gas analysis indexes (PaCO2, PaO2, pH value) were recorded immediately before extubation (T0), 5 minutes after extubation (T1), 10 minuites after extubation (T2), and 15 minutes after extubation (T3). The time of airway retention, the number of airway adjustment, the stay time pf PACU, and the comfort score during the course of ventilation after extubation were recorded. The adverse reactions were recorded.

Results Compared with group D, the HR of the patients in group C at T1 was higher (P < 0.05), the HR of the patients in groups K and C at T2 was higher (P < 0.05), the HR of the patients in group K at T3 was higher (P < 0.05), the MAP of the patients in groups K and B at T2 and T3 was higher (P < 0.05). Compared with T0, the HR of the patients in the four groups at T1 was lower (P < 0.05), the HR of the patients in group D at T2 was lower (P < 0.05), and those in groups in K and B at T3 was higher (P < 0.05). Compared with T0, the MAP of the patients in the four groups at T1 was lower (P < 0.05), the MAP of the patients in groups D and B at T2 was lower (P < 0.05), and those in groups K and B at T3 was higher (P < 0.05). Compared with the group D, the PaCO₂ of the patients in groups B and C at T3 was higher (P < 0.05), the PaO₂ of the patients in groups K, B and C at T1, T2 and T3 was lower (P < 0.05); the pH of the patients in group C at T2 was higher (P < 0.05), the pH of the patients in groups B and C at T3 was higher (P < 0.05). Compared with T0, the PaO₂ and pH in four groups were lower at T1-T3(P < 0.05), and the PaCO₂ were higher (P < 0.05). The PACU time of the patients in group C was longer than that in group D (P < 0.05). The comfort level of the patients in group D was better than those in groups K and group C (P < 0.05). Moreover, the incidence of restlessness in the group D was significantly lower than that in group C (P < 0.05).
Conclusion Dami weakly stimulated oropharyngeal pad can effectively manage patients’ airway, thus reducing adverse reactions and improving patients’ comfort, which has practical application value.